Toxicosis in First Trimester: What You Need to Know

If you are pregnant or planning to become pregnant, you may have heard of the term toxicosis. Toxicosis is a general term that refers to any condition caused by toxins or poisons in the body. In pregnancy, toxicosis can occur in two forms: early and late.

Early toxicosis, also known as nausea and vomiting of pregnancy (NVP) or morning sickness, is a common symptom that affects up to 80% of pregnant women. It usually starts around the 5th or 6th week of pregnancy and lasts until the end of the first trimester (12-13 weeks). Early toxicosis is not harmful to the mother or the baby, unless it becomes severe and leads to dehydration, electrolyte imbalance, ketosis, and weight loss. This condition is called hyperemesis gravidarum and affects about 1-2% of pregnant women. Hyperemesis gravidarum requires medical attention and treatment to prevent complications.

The causes of early toxicosis are not fully understood, but they may involve hormonal changes, neurologic factors, gastrointestinal factors, and psychological factors. Some factors that may increase the risk or severity of early toxicosis include:

– Having a history of NVP or motion sickness

– Having a twin or multiple pregnancy

– Having a hydatidiform mole (a type of abnormal pregnancy)

– Having a high-fat diet

– Having stress or anxiety

– Having a family history of NVP or hyperemesis gravidarum

The treatment of early toxicosis depends on the severity of the symptoms and the impact on the mother’s health and quality of life. Some general measures that may help include:

– Eating small, frequent meals and avoiding spicy, fatty, or odorous foods

– Drinking plenty of fluids and avoiding caffeine and alcohol

– Taking prenatal vitamins at night or with food

– Taking ginger supplements or drinking ginger tea

– Using acupressure bands or acupuncture

– Taking antihistamines, antacids, or vitamin B6 as recommended by your doctor

– Taking antiemetics (drugs that prevent nausea and vomiting) as prescribed by your doctor

Late toxicosis, also known as preeclampsia or eclampsia, is a serious complication that occurs in about 5% of pregnant women. It usually develops after the 20th week of pregnancy and is characterized by high blood pressure, proteinuria (protein in the urine), edema (swelling), and sometimes seizures. Late toxicosis can cause damage to the mother’s kidneys, liver, brain, and other organs, as well as fetal growth restriction, placental abruption, preterm birth, and stillbirth.

The causes of late toxicosis are also unknown, but they may involve problems with the placenta, immune system, blood vessels, genetics, or environmental factors. Some factors that may increase the risk of late toxicosis include:

– Having chronic hypertension, diabetes, kidney disease, or autoimmune disease

– Having a first pregnancy or a new partner

– Being older than 35 years or younger than 20 years

– Being obese or having a body mass index (BMI) higher than 30

– Having a family history of preeclampsia or eclampsia

The treatment of late toxicosis depends on the severity of the condition and the gestational age of the baby. The only definitive cure for late toxicosis is delivery of the baby and placenta. However, if the baby is not mature enough to survive outside the womb, the mother may need to be monitored closely and treated with medications to lower blood pressure, prevent seizures, and improve blood flow to the placenta. Sometimes, steroids may be given to speed up the baby’s lung development. If the condition becomes life-threatening for the mother or the baby, an emergency cesarean section may be done.

To prevent late toxicosis, it is important to have regular prenatal care and check-ups to monitor blood pressure, urine protein, weight gain, and fetal growth. Some lifestyle changes that may help include:

– Eating a balanced diet and limiting salt intake

– Drinking plenty of water and avoiding alcohol and tobacco

– Exercising moderately and regularly

– Managing stress and getting enough rest

– Taking low-dose aspirin as recommended by your doctor

To summarize, toxicosis in pregnancy can occur in two forms: early and late. Early toxicosis is common and usually mild, but it can become severe and require treatment. Late toxicosis is rare but serious and can cause complications for both mother and baby. Both conditions require medical attention and monitoring. By following your doctor’s advice and taking good care of yourself and your baby, you can reduce the risk of toxicosis and have a healthy pregnancy.

Check out our Did you Know? Section for more info – Morning Sickness

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